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Dr. Bill Yates
Affiliations
BIO (Biotechnology Industry Organization)
AAPS (American Association of Pharmaceutical Scientists),
CRS (Controlled Release Society)
Publications and Presentations
Ni Y, Tian L, Medi BM, Guo J, Turner D, Villaneueva I, Arden N, Quarles J, Tizard I, Yates K. An inactivated influenza whole virion nasal powder vaccine using Gelvac™ Powder Delivery System. Poster presented in the Business Forum Innovation Corridor, 2006 BIO Annual International Convention, Chicago, Illinois.
Yates, K. A novel inactivated nasal influenza vaccine. Presented at the 2006 World Vaccine Congress, Washington, D.C.
Ni Y, Tian L, Turner D, Villanueva I, Medi BM, Guo J, Arden N, Quarles J, Tizard I, Yates KM. Induction of protective immunity against influenza virus with a nasal powder vaccine delivery system (GelVac™). Poster presented at the 45th ICAAC Meeting, December 19, 2005, Washington, D.C.
Williamson D, Ni Y, Boudreaux B, Yates K. An in situ gelation study of dry powder GelVac™ formulations containing GelSite® Polymer, a well-characterized naturally occurring complex carbohydrate. Poster presented at the AAPS Annual Meeting, November 2005, Nashville, TN.
Yates KM, Ni Y. GelVac™ nasal powder: a new approach to vaccine delivery. Poster presented at BIO 2005 Annual International Convention, June 2005, Philadelphia, PA.
Stroud PA, Perry ES, Ni Y, Yates KM. Mucoadhesive property of the GelSite® polymer and the GelVac™ nasal vaccine delivery system. Poster presented at the 32nd Annual Meeting and Exposition of the Controlled Release Society, June 2005, Miami, FL.
Williamson D, Parker W, Yates K . Method validation of two critical release specifications for GelSite® polymer, an in-situ gel delivering vehicle. Poster presented at the AAPS National Biotechnology Meeting, June 2005, San Francisco, CA.
Tai-Nin Chow J, Williamson DA, Yates KM, Goux WJ. Chemical characterization of the immunomodulating polysaccharide of Aloe vera L. Carbohydrate Research, 2005 May 2; 340 (6): 1131-42.
Talmadge J, Chavez J, Jacobs L, Munger C, Chinnah T, Chow JT, Williamson D, Yates K. Fractionation of Aloe vera L. inner gel, purification and molecular profiling of activity. International Immunopharmacology, 2004 December 20; 4 (14): 1757-73.
Ni Y, Turner D, Yates KM, Tizard I. Isolation and characterization of structural components of Aloe vera L. leaf pulp. Int Immunopharmacol. 2004 Dec 20;4(14):1745-55.
Ni Y, Yates KM, and Tizard IR. Aloe Polysaccharides; Aloes: The genus Aloes by Tom Renolds. CRC - TAYLOR & FRANCIS, 2004.
Ni Y, Tian L, Turner D, Yates KM, Tizard I. An in-situ gelling nasal powder vaccine delivery system (GelVac). Poster presented at the 31st Annual Meeting and Exposition of the Controlled Release Society, June 2004, Honolulu, HI.
Stroud PA, Ni Y, Yates KM. Rheological characterization of the GelSite™ polymer for protein/peptide delivery. Poster presented at the 31st Annual Meeting and Exposition of the Controlled Release Society, June 2004, Honolulu, HI.
Ni Y, Tian L, Turner D, Yates KM, and Tizard I. An in-situ gelling inactivated influenza nasal powder vaccine. Data presented at the Influenza Vaccines for the World Conference (IVW), May 2004, Lisbon, Portugal.
Stroud PA, Carter C, Ni Y, Yates KM. Simultaneous quantitative detection of delivery vehicle and active protein agent by SEC-MALLS. Poster presented at the AAPS National Biotechnology Meeting, May 2004, Boston, MA.
Ni Y, Yates KM, Tizard I. Keratinocyte growth factor (KGF) and plasmin(ogen): an unique combination for enhanced wound healing. Poster presented at the AAPS National Biotechnology Meeting, May 2004, Boston, MA.
Egger SF, Brown GS, Kelsey LS, Yates KM, Rosenberg LJ, Talmadge JE. Hematopoietic augmentation by a β-(1,4)-linked mannan. Cancer Immunology and Immunotherapy, 1996, 43: 195-205
Egger SF, Brown GS, Kelsey LS, Yates KM, Rosenberg LJ, Talmadge JE. Studies on optimal dose and administration schedule of a hematopoietic stimulatory β-(1,4)-linked mannan. Int J Immunopharmacol. 1996 Feb;18(2):113-26.
King GK, Yates KM, Greenlee, PG, Pierce KR, Ford CR, McAnalley BH, Tizard, IR. The effect of Acemannan Immunostimulant in combination with surgery and radiation therapy on spontaneous canine and feline fibrosarcomas. J Am Anim Hosp Assoc. 1995 Sep-Oct;31(5):439-47.
Kemp MC, Marshall GD, Chinnah AD, Yates KM, Rosenberg LJ, Tizard IR, McAnalley BH. In vitro and in vivo immunological effects of acemannan, a polydispersed b-(1,4)-linked acetylated mannan. Presented at Immunopotentiators in Modern Vaccines Conference. Pasteur Institute, Paris, France, September 7-9, 1993.
Yates KM, Kemp MC, Ni Y, Raboud J, Ford CR, Tizard IR. A comparison of the effects of acemannan (ACM) given by three routes of administration to feline immunodeficiency virus (FIV)-infected cats. Poster presented at IXth International Conference on AIDS/IVth STD World Congress, January 1993.
Yates KM, Raboud J, Tizard I. Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus. Poster presented at 2nd Annual Canadian National Conference on HIV/AIDS Research. September, 1993.
Yates KM, Rosenberg LJ, Harris CK, Bronstad DC, King GK, Biehle GA, Walker B, Ford CR, Hall JE, Tizard IR. (1992) Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus. Vet. Immunol. Immunopathol. 35:177-189.
Rosenberg LJ and Yates KM. Improved feline peripheral blood mononuclear cell preparation for flow ytometry. Abstract presented at First International Conference of Feline Immunodeficiency Virus Researchers. University of California, Davis, California, September 4-7, 1991.
Carpenter RH, Harris CK, Bronstad DC, King G, Biehle GA, Walker BW, Yates KM, Tizard IR. Effect of acemannan in treatment of feline immunodeficiency virus-infected cats. Abstract presented at First International Conference of Feline Immunodeficiency Virus Researchers. University of California, Davis, California, September 4-7, 1991.
Yates KM, Carpenter RH, Harris CK, Bronstad DC, Biehle GA, Walker BW, King GK. Use of acemannan in treatment of feline immunodeficiency virus disease. Abstract presented at Veterinary Cancer Society 11th Annual Conference. Minneapolis, Minnesota, October 27-29, 1991.
Harris C, Pierce K, King G, Yates KM, Hall J, Tizard I. Efficacy of acemannan in treatment of canine and feline spontaneous neoplasms. (1991) Mol. Biother. 3:207-213.
U.S. Patents
Dried Hydrogel From Hydrophilic-Hygroscopic Polymer. U.S. Patent No. 5,409,703
Uses of Denture Adhesive Containing Aloe Extract. U.S. Patent No. 5,760,102
Bioactive Factors of Aloe Vera Plants. U.S. Patent No. 5,902,796
Aloe Pectins. U.S. Patent No. 5,929,051
Pectin Substance as a Growth Factor Stabilizer. U.S. Patent Nos. 6,274,548 and 6,313,103
In Situ Gel Formation of Pectin. U.S. Patent No. 6,777,000
Pharmacological Compositions Comprising Pectins having High Molecular Weights and
Low degrees of Methoxylation. U.S. Patent No. 7,022,683
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