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Faculty

Benjamin BrunerBenjamin F. Bruner, Ph.D., M.B.A.
Chair, Department of Biology
Office: Pryor-England 164B
Phone: 501-279-4829
bbruner1@harding.edu 
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Teaching and Research Interests

My research interests have focused on examining the diversity that exists in patients with a variety of autoimmune diseases, but my primary focus has been centered on the study of systemic lupus erythematosus (SLE).  My training in the Department of Pathology at the University of Oklahoma Health Sciences Center and in the Department of Clinical Immunology at the Oklahoma Medical Research Foundation has allowed me to study both the fundamentals of cellular and molecular biology and the impact that abnormalities in those systems has on human health. 

As a result, I teach a wide variety of courses including Human Anatomy and Physiology (BIOL 249), Cell Biology (BIOL 259), Microbiology (BIOL 271), and Pathophysiology (BIOL 314) just to name a few.  I also enjoy serving as a mentor for students preparing for their Senior Seminar (BIOL 440) presentations.

Links

University of Oklahoma Health Sciences Center

Oklahoma Medical Research Foundation

Selected Publications

Selected Publications

Bruner BF, Guthridge JM, Lu R, Vidal G, Kelly JA, Robertson JM, Kamen DL, Gilkeson GS, Neas BR, Reichlin M, Scofield RH, Harley JB, James JA.  Comparison of autoantibody specificities and clustering between traditional and bead-based autoantibody assays in a large, ethnically diverse collection of SLE patients and family members.  2012.  Arthritis and Rheumatism.  64(11), 3677-3686. PMID: 23112091

Lu R, Robertson JM, Bruner BF, Guthridge JM, Neas BR, Nath SK, Kelly JA, Moser Sivils KL, Chakravarty EF, Kamen DL, Gilkeson GS, Wallace DJ, Weisman MH, Scofield RH, Harley JB, James JA.  Multiple autoantibodies display association with lymphopenia, proteinuria, and cellular casts in a large, ethnically diverse SLE patient cohort.  2012.  Autoimmune Diseases. (2012) Article ID 819634, 1-11. PMID: 22988489

Bruner BF, Vista ES, Wynn DM, James JA.  Epitope specificity of anti-myeloperoxidase antibodies: Identification of human immunodominant epitopes.  2011. Clinical and Experimental Immunology.  164(3), 330-336. PMID: 21401576.

Bruner BF, Vista ES, Wynn DM, Harley JB, James JA.  Anti-neutrophil cytoplasmic antibodies target sequential functional proteinase-3 epitopes in the sera of patients with Wegener’s granulomatosus. 2010.  Clinical and Experimental Immunology. 162(2), 262-270. PMID: 21077276.

Aggarwal R, Namjou B, Li S, D'Souza A, Tsao BP, Bruner BF, James JA, Scofield RH. Male only systemic lupus. 2010.  Journal of Rheumatology. 37(7), 1480-1487. PMID: 20472921.

Heinlen LD, McClain MT, Ritterhouse LL, Bruner BF, Edgerton CC, Keith MP, James JA, Harley JB.  60kD Ro and nRNP A frequently initiate human lupus autoimmunity.  2010. PLoS ONE. 5(3), e9599. PMID: 20224770.

James JA, Kim-Howard XR, Bruner BF, Jonsson MK, McClain MT, Arbuckle MR, Walker C, Dennis GJ, Merrill JT, Harley JB.  Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus.  2007. Lupus. 16(6), 401-409. PMID: 17664230.

McClain MT, Poole BD, Bruner BF, Kaufman KM, Harley JB, James JA.  An altered immune response to Epstein-Barr virus nuclear antigen-1 (EBNA-1) in pediatric systemic lupus erythematosus. 2006. Arthritis and Rheumatism. 54(1), 360-368. PMID: 16385527.

Bruner BF, Wynn DM, Reichlin M, Harley JB, James JA. Humoral antigenic targets of the ribosomal p0 lupus autoantigen are not limited to the carboxyl region.  2005.  Annals of the New York Academy of Sciences. 1051, 390-403. PMID: 16126981.

Steven Cooper

Steven M. Cooper, Ph.D.
Assistant Professor of Biology
Office: Pryor-England 164C
Phone: 501-279-5281
scooper@harding.edu

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Teaching and Research Interests

My interest in the world around me began as a child, when I grew up reading National Geographic. It seems that wherever I found myself, I was picking up some rock or insect, or watching the world around me awed by the variety of living things and their interactions with the world. This fascination remained with me through high school and led me to eventually begin my higher education at Harding University where I earned a Bachelor of Science degree in Biology. Following graduation , I enrolled in Stephen F. Austin State University in the Biology program where I worked towards a Masters of Science in Aquatic Biology.   I have always been concerned with the effects of man on animal life and the environment.  Eventually I enrolled in University of Arkansas for Medical Sciences where I received my Ph.D. in Interdisciplinary Toxicology.  

My education and training have equipped me with insight, knowledge of methods, and tools that have allowed me to observe the creation to a degree I never thought possible. My interests center around how external factors in the environment affect an animals' responses to exogenous chemicals.

Many of my past professors inspired me to examine the world around me and to critically think.  They planted the seeds in me that led me to aspire to teach. Now that I am in the classroom, I hope that through the courses I teach that I might help my students curiosity to grow and inspire them to delve deeper into the study of God's handiwork.

Links

Society of Toxicology

UAMS: Department of Pharmacology and Toxicology

Selected Publications

Steven Cooper, John R. Latendresse, Daniel R. Doerge, Nathan C. Twaddle, Xin Fu and K. Barry Delclos. 2006. Dietary Modulation of p-Nonylphenol–Induced Polycystic Kidneys in Male Sprague-Dawley Rats. Toxicological Sciences 2006 91(2):631-642

Ron DoranRon Doran, M.S.
Professor of Biology
Office: Pryor-England 135
Phone: 501-279-4705
doran@harding.edu  
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Teaching and Research Interests

I am currently working on the Vascular Flora of Arkansas Project along with 16 other taxonomists from around the state. This is a 10 year project with a goal of producing a definitive treatment of the vascular flora of Arkansas. We have just printed the first of three publications to that end; Checklist of the Vascular Plants of Arkansas. The next publication will be an atlas and the third and final publication will be an illustrated manual. My other interests include animal/plant interactions and environmental science especially sustainable development. My interest in sustainable development came about from visiting several developing countries in South and Central America on campaigns and working one summer with Clinica Christiana in Quetzaltenango, Guatemala, and also from teaching environmental science. My teaching responsibilities at Harding include Botany, Plant Taxonomy, Ecology, and Environmental Science.

Links

Arkansas Native Plant Society

Arkansas Vascular Flora Project

Arkansas Biodiversity-Vascular Plants

 Amy Ellis

Amy Ellis, B.A.
Instructor of Biology
Office: Pryor-England 216
Phone: 501-279-2985
aellis2@harding.edu  

 

Joseph GoyJoseph W. Goy, Ph. D. 
Associate Professor of Biology 
Office: Pryor-England 161A
Phone: 501-279-4515
jwgoy@harding.edu
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Teaching and Research Interests 

My teaching responsibilities at Harding include General Zoology, Marine Biology, Ecology, Invertebrate Zoology, and Environmental Science.  I also participate in several team-taught courses including Animal Physiology, Parasitology, Ecology Lab, Animal Behavior, and Seminar.

My research centers around the systematics, larval development, zoogeography, population genetics, ecology and ethology of decapod crustaceans, especially stenopodidean and caridean shrimps.  My primary research focus includes: (1) use of larval morphological characteristics in the phylogenetic analysis of decapod crustaceans; (2) determination of biochemical cues in metamorporically competent larvae of commensal shrimps and crabs; (3) examination of population genetics of decapods with circumtropical distributions; and (4) mate recognition and pair bonding in decapods.  Studies readily involve students in undergraduate research in numerous aspects of the above topics.

Links

Crustacean Society

Zootaxa

Selected Publications

Selected Publications

Goy, Joseph W.  2005.  Stenopodid Shrimps. In: Camarones, Langostes y Cangrejos de la Costa Este de México.  Volumen I. [Shrimps, Lobsters and Crabs of the Eastern Coast of Mexico. Volume I] J.L. Hernández Aquilera, J.A. Ruiz Muño, R.E. Toral Almazán and V.A. Fuentes (eds.) Estudio y Conservación de La Naturaleza, A.C. y Comisión Nacional para el Concimiento y Uso de la Biodiversidad.  México. 350pp.

Martin, Joel M. and Joseph W. Goy.  2004.  The first larval stage of Microprostehema semilaeve (Von Martens, 1872) (Crustacea: Decapoda: Stenopodidea) obtained in the laboratory.  Gulf and Caribbean Research 16: 19-25.

Goy, Joseph W.  1992.  Systematics and Zoogeography of Eastern Pacific Stenopodidean Shrimps (Crustacea: Decapoda).  Proceedings of the San Diego Society of Natural History.  22: 1-6.

Goy, Joseph W.  1992.  A new species of Stenopus from Australia, with a redescription of Stenopus cyanoscelis (Crustacea: Decapoda: Stenopodidea).  Journal of Natural History 26(10: 79-102.

Morgan, Steven G., Joseph W. Goy and John D. Costlow, Jr.  1988.  Effects of density, sex ratio, and refractory period on spawning of the mud crab, Rhithropanopeus harrisii in the laboratory.  Journal of Crustacean Biology 8(2): 245-249.

Jo Goy

Jo M. Goy, Ph.D.
Assistant Professor of Biology
Office: Pryor-England 164E
Phone: 501-279-4151
jmgoy@harding.edu 

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Teaching and Research Interests

 I have had the good fortune of studying biology from both an organismal/ecology and cell/molecular perspective. I gained my first research experience as an undergraduate student examining prey selection in water snakes. Planning a lifework in ecology, I completed a master's degree in the area of behavioral ecology. However, when my husband and I moved to Texas A&M, I began a career path very divergent from snakes and behavior. At TAMU I was privileged to work with Dr. Loren Skow, and learn the science and art of molecular genetics. After 11 years working with DNA, I joined the faculty at HU and began a tenure in teaching. My primary teaching responsibilities include Cell Biology, Cell and Molecular lab, Molecular and Cellular Biology and coordinating Senior Biology Seminar. I also participate in Developmental Biology, Animal Physiology, and occasionally Genetics.

Links

NCBI

Selected Publications

Selected Publications

L. A. Nemec, L. C. Skow, J. M. Goy and D. C. Kraemer. 1989. Introduction of DNA into murine embryos by electroporation. Theriogenology, Volume 31, Issue 1.

M. L. Reed, C. G. Dorn, J. M. Goy, L. C. Skow and D. C. Kraemer. 1989. Survival of bovine blastocysts microinjected with liposome-encapsulated DNA. Theriogenology, Volume 31, Issue 1.

R. G. Jaeger, J. M. Goy, M. Tarver and C. E. Márquez. 1986. Salamander territoriality: pheromonal markers as advertisement by males. Animal Behaviour, Volume 34, Issue 3.

Amber Hug

Amber Hug, M.Ed.
Instructor of Biology
Office: Pryor-England 156/216
Phone: 501-279-4459
ahug1@harding.edu

T Lee

Trixie Lee, Ph.D.
Assistant Professor of Biology
Office: Pryor-England 166A
Phone: 501-279-4508
tnlee@harding.edu 

Nathan MillsNathan E. Mills, Ph.D. 
Associate Professor of Biology
Office: Pryor-England 161B
Phone: 501-279-4536
nmills@harding.edu
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Teaching and Research Interests 

My general research interest is in understanding how the environment affects amphibian development and growth. My research has focused on two specific questions. First, how does hypoxia affect embryonic growth and development, and in turn, how does the embryo adaptively respond to hypoxia through changes in egg capsule oxygen conductance. I currently have undergraduate students involved in this research. And second, how do pesticides interact with environmental variables, such as competition and predation, to alter the survival and growth of amphibian larvae and the timing of metamorphosis. In addition to my primary research interest, I am involved in an amphibian survey at the Bald Knob National Wildlife Refuge near Bald Knob, Arkansas, and I have had the privilege of collaborating with Mike Plummer on research investigating the behavioral ecology of turtles and snakes.

My teaching responsibilities at Harding University include Human Anatomy and Physiology, Ornithology, and Ecology. I am also involved in team teaching Developmental Biology.

Links

The Ecological Society of America

Partners in Amphibian and Reptile Conservation

All About Birds

Selected Publications

Selected Publications

Wrensch*, Z. C. and N.E. Mills. In Preparation. Bufo fowleri alters its attraction to light I the presence of a potential predator.

Van Dyke, J.U., M.V. Plummer, S.J. Beaupre, T.N. Lee*, and N.E. Mills. In Preparation. Metabolic rate of hatchling softshell turtles, Apalone mutica.

Plummer, M.V. and N.E. Mills. In Preparation. Growth of Spiny Softshell Turtles (Apalone spinifera).

Plummer, M.V. and N.E. Mills. In Preparation. Body temperatures of Hognose Snakes (Heterodon platirhinos).

Plummer, M.V., T.N. Lee*, and N.E. Mills. 2008. The effect of a sand substrate on the growth and condition of Apalone mutica hatchlings. Journal of Herpetology 42:550-554. (Link)

Plummer, M.V., D.G. Krementz, L.A. Powell, and N.E. Mills. 2008. Effects of habitat disturbance on survival rates of softshell turtles (Apanone spinifera) in an urban stream. Journal of Herpetology 42:555-563. (Link)

Plummer, M.V. and N.E. Mills. 2008. Structure of an urban population of softshell turtles (Apalone spinifera) before and after stream degradation. In J.C. Mitchell, R.E. Jung Brown, and B. Bartholomew (eds.) Urban Herpetology. Herpetological Conservation Vol. 3. Society for the Study of Amphibians and Reptiles. Salt Lake City, UT. (Link)

Valls*, J.H. and N.E. Mills. 2007. Intermittent hypoxia in eggs of Ambystoma maculatum: Embryonic development and egg capsule conductance. Journal of Experimental Biology 210:2430-2435. (Link)

Lee*, T.N., M.V. Plummer, and N.E. Mills. 2007. Use of posthatching yolk and external forage to maximize early growth in Apalone mutica hatchlings. Journal of Herpetology 41:492-500. (Link)

Plummer, M.V. and N.E. Mills. 2006. Heterodon platirhinos (Eastern Hognose Snake) road crossing behavior. Herpetological Review 37:352. (Link)

Plummer, M.V., T.L. Crabill, N.E. Mills, and S.L. Allen. 2005. Body temperatures of free-ranging softshell turtles (Apalone spinifera) in a small stream. Herpetological Review 36:371-375. (Link)

Mills, N.E. and R.D. Semlitsch. 2004. Competition and predation mediate the indirect effects of an insecticide on southern leopard frogs. Ecological Applications 14:1041-1054. (Link)

Mills, N.E., M.C. Barnhart, and R. Semlitsch. 2001. Effects of hypoxia on egg capsule conductance in Ambystoma (class Amphibia, order Caudata). Journal of Experimental Biology 204:3747-3753. (Link)

Relyea, R.A. and N.E. Mills. 2001. Predator-induced stress makes the pesticide carbaryl more deadly to gray treefrog tadpoles (Hyla versicolor). Proceeding of the National Academy of Science 98:2491-2496. (Link)

Plummer, M.V. and N.E. Mills. 2000. Spatial ecology and survivorship of resident and translocated hognose snakes (Heterodon platirhinos). Journal of Herpetology 34:565-575. (Link)

Mills, N.E. and M.C. Barnhart. 1999. Effects of hypoxia on embryonic development in two Ambystoma and two Rana species. Physiological and Biochemical Zoology 72:179-188. (Link)

Plummer, M.V., N.E. Mills, and S.L. Allen. 1997. Activity, habitat, and movement patterns of softshell turtles (Trionyx spiniferus) in a small stream. Chelonian Conservation and Biology 2:514-420. (Link)

Plummer, M.V. and N.E. Mills. 1996. Observations on trailing and mating behaviors in hognose snakes (Heterodon platirhinos). Journal of Herpetology 30:80-82. (Link)

* indicates undergraduates whose research was advised or co-advised by me.

John Moon

Dr. John W. Moon, Jr.
Professor of Biology
Office: Pryor-England 164A
Phone: 501-279-4459
moon@harding.edu

Rebekah RampeyRebekah A. Rampey, Ph.D.
Associate Professor of Biology
Office: Pryor-England 164D
Phone: 501-279-5497
rrampey@harding.edu
More Info...

Teaching and Research Interests

I obtained my Ph.D. in Biochemistry and Cell Biology at Rice University (Houston, Texas) in 2004. In the fall of 2006, I became a Howard Hughes Participating Faculty member and collaborate with HHMI Professor Bonnie Bartel at Rice. Dr. Bartel was awarded a one million dollar grant from HHMI to develop a program integrating undergraduate classes with research. This grant supports the development of a laboratory course at HU (BIOL 371) in which students work on individual research projects in plant molecular biology. In addition, funding is provided for selected students to continue and expand these projects by working with Dr. Bartel during the summer. Our research interests focus on auxins, a class of phytohormones affecting virtually every aspect of plant development. Plants regulate auxin levels through complex interactions among de novo synthesis, degradation, influx, efflux, and conjugate synthesis and hydrolysis. A thorough knowledge of these pathways is key to understanding auxin influences on plants. We are using genetic approaches to understand the function and metabolism of auxin conjugates in the model plant Arabidopsis thaliana.

Links

Bartel Lab

Selected Publications

Selected Publications

Rampey, R.A., Woodward, A.W., Hobbs, B.N., Tierney, M.P., Lahner, B., Salt, D.E. and Bartel, B. An Arabidopsis basic helix-loop-helix leucine zipper protein modulates metal homeostasis and auxin conjugate responsiveness. Genetics, in press.

López-Bucio, J., Hernández-Abreu, E., Sánchez-Calderón, L., Pérez-Torres, A., Rampey, R.A.,  Bartel, B., and Herrera-Estrella, L.  An auxin transport independent pathway is involved in phosphate stress-induced root architectural alterations in Arabidopsis:  Identification of BIG as a mediator of auxin in pericycle cell activation.  Plant Physiology 137:  681-691, 2005.

Rampey, R.A., LeClere, S., Kowalczyk, M., Ljung, K., Sandberg, G., and Bartel, B.  A family of  auxin-conjugate hydrolases that contribute to free indole-3-acetic acid levels during Arabidopsis germination. Plant Physiology 135:  978-988, 2004.

LeClere, S., Rampey, R.A., and Bartel, B.  IAR4, a gene required for auxin conjugate sensitivity in Arabidopsis, encodes a pyruvate dehydrogenase E1a homolog.  Plant Physiology135: 989-999, 2004.

LeClere, S., Tellez R., Rampey R.A., Matsuda S.P.T., Bartel, B. Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis.  Journal of  Biological Chemistry.  23:  20446-52, 2002.

Donald SandersDon E. Sanders, M.Ed., M.S., MT(ASCP)
Assistant Professor of Biology 
Office: Pryor-England 163
Phone: 501-279-4851
dsanders2@harding.edu
More Info...

Teaching and Research Interests

After a few years as a licensed medical technologist, I pursued both an M.Ed and an M.S. in biology and went on to serve as a clinical instructor in medical technology at two schools in Memphis, later moving to laboratory management. When I decided to leave lab management, my career choice still centered on the practical application of science, and for fourteen years I traveled the southeastern United States as a blood chemistry specialist for Beckman Instruments. In 1996, tired of the travel and wishing to return to the classroom, I began teaching Advanced Placement Biology at Memphis Harding Academy, eventually adding an anatomy and physiology class to the curriculum and serving as Science Division Head. In 2005, my wife, Patti, and I relocated to Searcy where I began serving as an adjunct faculty member at Harding.  Although I thoroughly enjoyed my master's work researching the reproductive potential of the cave salamander, Eurycea lucifuga, I now focus on my special interest of anatomy and physiology. I find the human body fascinating, and try to help my students see the glory of God's wonderful creation through the study of anatomy and physiology.  Classes I have taught include General Biology, Microbiology, A&P I and A&P II. Patti and I enjoy visiting our children and grandchildren in Alaska and Florida each summer.  Fishing and golfing are my favorite recreational pursuits.

Links

The American Physiological Society

American Association of Anatomists

Get Body Smart.com

Department of Biology

Campus Box 12251
Pryor-England Science Center 
Harding University
Searcy, AR 72149-12251

Phone: 501-279-4459
Fax: 501-279-4706